Incomplete penetrance
The concept that even though several members of a family or population may have the same DNA mutation, not everyone with that mutation will have or develop the disease. This is in contrast to variable expressivity which means that people with the same disease have varying disease severity. Penetrance, in contrast, is more of a yes/no question ? does or does not the person have the disease.
Related Links
Reduced penetrance in human inherited disease – ScienceDirect
Penetrance, Variable Expressivity, and Gene Modifiers — Learn Science at Scitable
Understanding genetics: What are “penetrance” and “expressivity”? – Helix Blog
Incomplete penetrance of biallelic ALDH1A3 mutations. – PubMed – NCBI
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